Dioxin & Furan AGAT's Brand New State of the Art HRMS
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This is a very exciting time for AGAT, as we enter
the expanding market of Ultra-Trace Chemistry; which can easily be dovetailed
into Ultra-Trace analysis of PAH's and Polybrominated Diphenylethers (PBDPE)
What are Dioxins and Furans?
PCDD/DF's are a family of compounds that make up 217 geometric isomers called congeners. These compounds do not occur in nature, and are not intentionally produced, but are the bi-products of chemical processes such as municipal waste incineration, smelting processes, and the preparation of polyvinyl chloride (PVC) plastics. PCDD/DF's are very resistant to chemical degradation, and have a half-life of approximately 7 years. They are released during the above-mentioned processes into the atmosphere, and subsequently enter the waste cycle, and hence the food chain. Dioxins and Furans are also VERY lipid soluble, and bio-accumulate.
While all PCDD's and PCDF's are toxic to some degree, the most toxic is
2,3,7,8-Tetrachloro-p-dioxin. This compound is the most toxic chemical known to
man. The actual mechanism of its toxicity is at, present unknown, but is
believed to be linked to the positions of the attached chlorine atoms in the
2,3,7,8, positions.
As such of the 217 possible congeners, there are only 17 congeners that have
chlorine in the 2,3,7,8 positions and these are thought to be the most toxic.
Dioxin/Furan exposure can cause a host of adverse health effects such as:
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Immune system degradation/failure
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Nervous system degradation/failure
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Birth Defects
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Chloracne (a skin condition that causes terrible scarring)
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Cancer
AGAT is expanding its scope of analyses to include Polychlorinated
Dibenzodioxins (PCDD), and Polychlorinated dibenzofurans (PCDF).
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AGAT is expanding its scope of analyses to include Polychlorinated Dibenzodioxins (PCDD), and Polychlorinated dibenzofurans (PCDF).
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How can we detect that Small an Amount?
Dioxins and Furans are analyzed by use of High Resolution Gas Chromatography/Mass Spectrometry. AGAT currently possesses the Waters/Micromass Autospec Premier HRGC/MS. This instrument is the flagship of the Waters instrument line, and possesses unprecedented resolving power and detection limits. The Autospec Premier uses magnetic sector double focusing technology. The ion beam is focused after it leaves the source and before it enters the magnetic field; it is the analyzed, and re-focused before it enters the detector. This process affords resolving power up to 50 000 60 000. This mean that this instrument can accurately resolve a molecule with a molecular weight of 50 000 amu from another molecule having a molecular weight of 50 001 amu. We can accurately detect concentrations of 80 pg/L (ppq).
For more information about Dioxins and Furans, please contact Paul Houle at
(403) 735-2552
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